The way in which research is carried out is undergoing a series of radical changes as a result of the digital revolution. Researchers in all disciplines are increasingly adopting digital tools, techniques and practices in communities and projects that span multiple disciplines, laboratories, organisations, and national boundaries. eScience 2017 brings together leading international and interdisciplinary research communities, developers, and users of eScience applications and enabling IT technologies. The conference serves as the premier forum to present the results of the latest research and product/tool developments and to highlight related activities from around the world.